A versatile synthetic dimerizer for the regulation of protein–protein interactions

The use of low molecular weight organic compounds to induce dimerization or oligomerization of engineered proteins has wide-ranging utility in biological research as well as in gene and cell therapies. Chemically induced dimerization can be used to activate intracellular signal transduction pathways...

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Bibliografiska uppgifter
Huvudupphovsmän: Amara, Jane F., Clackson, Tim, Rivera, Victor M., Guo, Tao, Keenan, Terence, Natesan, Sridaran, Pollock, Roy, Yang, Wu, Courage, Nancy L., Holt, Dennis A., Gilman, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC23423/
https://ncbi.nlm.nih.gov/pubmed/9380684
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