A versatile synthetic dimerizer for the regulation of protein–protein interactions

The use of low molecular weight organic compounds to induce dimerization or oligomerization of engineered proteins has wide-ranging utility in biological research as well as in gene and cell therapies. Chemically induced dimerization can be used to activate intracellular signal transduction pathways...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Amara, Jane F., Clackson, Tim, Rivera, Victor M., Guo, Tao, Keenan, Terence, Natesan, Sridaran, Pollock, Roy, Yang, Wu, Courage, Nancy L., Holt, Dennis A., Gilman, Michael
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23423/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10618
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