Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery.
We report the generation of a retroviral vector that infects human cells specifically through recognition of the low density lipoprotein receptor. The rationale for this targeted infection is to add onto the ecotropic envelope protein of Moloney murine leukemia virus, normally trophic for murine cel...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7570 |
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