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Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1

The current studies explore the mechanism by which the sphingomyelin content of mammalian cells regulates transcription of genes encoding enzymes of cholesterol synthesis. Previous studies by others have shown that depletion of sphingomyelin by treatment with neutral sphingomyelinase causes a fracti...

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Bibliografski detalji
Glavni autori: Scheek, Sigrid, Brown, Michael S., Goldstein, Joseph L.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC23408/
https://ncbi.nlm.nih.gov/pubmed/9326582
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