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A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme

Genetic disruption of the Saccharomyces cerevisiae C-4 sterol methyl oxidase ERG25 gene leads to sterol auxotrophy. We have characterized a suppression system that requires two mutations to restore viability to this disrupted strain. One suppressor mutation is erg11, which is blocked in 14α-demethyl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gachotte, D., Pierson, C. A., Lees, N. D., Barbuch, R., Koegel, C., Bard, M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences of the USA 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC23406/
https://ncbi.nlm.nih.gov/pubmed/9326581
Tagiau: Ychwanegu Tag
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