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Expression, purification and preliminary X-ray diffraction studies of RebC

The flavin-dependent monooxygenase RebC is a key enzyme in the biosynthesis of the indolocarbazole rebeccamycin. The synthesis of rebeccamycin is of great interest as it has been shown to be a natural antitumour agent. The enzyme has been recombinantly expressed in Escherichia coli and purified to h...

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Main Authors: van Staalduinen, Laura M., Bhattacharya, Anupam, Groom, Katherine, Zechel, David L., Jia, Zongchao
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2339749/
https://ncbi.nlm.nih.gov/pubmed/18007056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107051640
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