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Purification, crystallization, X-ray diffraction analysis and phasing of an engineered single-chain PvuII restriction endonuclease

The restriction endonuclease PvuII from Proteus vulgaris has been converted from its wild-type homodimeric form into the enzymatically active single-chain variant scPvuII by tandemly joining the two subunits through the peptide linker Gly-Ser-Gly-Gly. scPvuII, which is suitable for the development o...

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Detalhes bibliográficos
Main Authors: Meramveliotaki, Chrysi, Kotsifaki, Dina, Androulaki, Maria, Hountas, Athanasios, Eliopoulos, Elias, Kokkinidis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2339719/
https://ncbi.nlm.nih.gov/pubmed/17909283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107040377
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