Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A(3)/J(3)-Isoprostanes) in Vivo from Eicosapentaenoic Acid

Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) found in marine fish oils are known to suppress inflammation associated with a wide variety of diseases. Eicosapentaenoic acid (EPA) is one of the most abundant ω-3 fatty acids in fish oil, but the mechanism(s) by which EPA exerts its beneficial effe...

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Detalhes bibliográficos
Main Authors: Brooks, Joshua D., Milne, Ginger L., Yin, Huiyong, Sanchez, Stephanie C., Porter, Ned A., Morrow, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335341/
https://ncbi.nlm.nih.gov/pubmed/18263929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800122200
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