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Using quality scores and longer reads improves accuracy of Solexa read mapping

BACKGROUND: Second-generation sequencing has the potential to revolutionize genomics and impact all areas of biomedical science. New technologies will make re-sequencing widely available for such applications as identifying genome variations or interrogating the oligonucleotide content of a large sa...

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Detalhes bibliográficos
Main Authors: Smith, Andrew D, Xuan, Zhenyu, Zhang, Michael Q
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335322/
https://ncbi.nlm.nih.gov/pubmed/18307793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-128
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