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Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions

BACKGROUND: The risk of common diseases is likely determined by the complex interplay between environmental and genetic factors, including single nucleotide polymorphisms (SNPs). Traditional methods of data analysis are poorly suited for detecting complex interactions due to sparseness of data in hi...

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Detalhes bibliográficos
Main Authors: Mechanic, Leah E, Luke, Brian T, Goodman, Julie E, Chanock, Stephen J, Harris, Curtis C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335300/
https://ncbi.nlm.nih.gov/pubmed/18325117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-146
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