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Method for the isolation of Escherichia coli K-12 mutants deficient in essential genes.

We developed a general procedure for the induction and identification of mutations in chromosomal essential genes that are located in a diploid region of Escherichia coli K-12. The partial diploidy is conferred by an episome that is temperature sensitive for replication so that a mutant strain will...

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Hlavní autoři: Armstrong, K A, Herman, R K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1976
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC233257/
https://ncbi.nlm.nih.gov/pubmed/770428
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