‘Protected DNA Probes’ capable of strong hybridization without removal of base protecting groups

We propose a new strategy called the ‘Protected DNA Probes (PDP) method’ in which appropriately protected bases selectively bind to the complementary bases without the removal of their base protecting groups. Previously, we reported that 4-N-acetylcytosine oligonucleotides (ac(4)C) exhibited a highe...

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Autori principali: Ohkubo, Akihiro, Kasuya, Rintaro, Sakamoto, Kazushi, Miyata, Kenichi, Taguchi, Haruhiko, Nagasawa, Hiroshi, Tsukahara, Toshifumi, Watanobe, Takuma, Maki, Yoshiyuki, Seio, Kohji, Sekine, Mitsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330233/
https://ncbi.nlm.nih.gov/pubmed/18272535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm927
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