‘Protected DNA Probes’ capable of strong hybridization without removal of base protecting groups

We propose a new strategy called the ‘Protected DNA Probes (PDP) method’ in which appropriately protected bases selectively bind to the complementary bases without the removal of their base protecting groups. Previously, we reported that 4-N-acetylcytosine oligonucleotides (ac(4)C) exhibited a highe...

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Detalles Bibliográficos
Autores principales: Ohkubo, Akihiro, Kasuya, Rintaro, Sakamoto, Kazushi, Miyata, Kenichi, Taguchi, Haruhiko, Nagasawa, Hiroshi, Tsukahara, Toshifumi, Watanobe, Takuma, Maki, Yoshiyuki, Seio, Kohji, Sekine, Mitsuo
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330233/
https://ncbi.nlm.nih.gov/pubmed/18272535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm927
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