‘Protected DNA Probes’ capable of strong hybridization without removal of base protecting groups

We propose a new strategy called the ‘Protected DNA Probes (PDP) method’ in which appropriately protected bases selectively bind to the complementary bases without the removal of their base protecting groups. Previously, we reported that 4-N-acetylcytosine oligonucleotides (ac(4)C) exhibited a highe...

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Detalhes bibliográficos
Main Authors: Ohkubo, Akihiro, Kasuya, Rintaro, Sakamoto, Kazushi, Miyata, Kenichi, Taguchi, Haruhiko, Nagasawa, Hiroshi, Tsukahara, Toshifumi, Watanobe, Takuma, Maki, Yoshiyuki, Seio, Kohji, Sekine, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330233/
https://ncbi.nlm.nih.gov/pubmed/18272535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm927
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