Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression

BACKGROUND: At early stages of infection CCR5 is the predominant HIV-1 coreceptor, but in approximately 50% of those infected CXCR4-using viruses emerge with disease progression. This coreceptor switch is correlated with an accelerated progression. However, those that maintain virus exclusively rest...

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Главные авторы: Borggren, Marie, Repits, Johanna, Kuylenstierna, Carlotta, Sterjovski, Jasminka, Churchill, Melissa J, Purcell, Damian FJ, Karlsson, Anders, Albert, Jan, Gorry, Paul R, Jansson, Marianne
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330154/
https://ncbi.nlm.nih.gov/pubmed/18371209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-28
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