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Crystallization and preliminary X-ray crystallographic analysis of the receptor-uncoupled mutant of Gα(i1)
In order to understand the molecular mechanisms by which G-protein-coupled receptors (GPCRs) activate G proteins, the K349P mutant of Gα(i1) (K349P), which is unable to couple to the muscarinic acetylcholine receptor, was prepared and its crystals were grown along with those of wild-type Gα(i1) prot...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2330130/ https://ncbi.nlm.nih.gov/pubmed/17277460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107003363 |
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