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Preservation of Muscle Force in Mdx3cv Mice Correlates with Low-Level Expression of a Near Full-Length Dystrophin Protein

The complete absence of dystrophin causes Duchenne muscular dystrophy. Its restoration by greater than 20% is needed to reduce muscle pathology and improve muscle force. Dystrophin levels lower than 20% are considered therapeutically irrelevant but are associated with a less severe phenotype in cert...

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Bibliografske podrobnosti
Main Authors: Li, Dejia, Yue, Yongping, Duan, Dongsheng
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329842/
https://ncbi.nlm.nih.gov/pubmed/18385524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071042
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