An Allele-Specific RT-PCR Assay to Detect Type A Mutation of the Nucleophosmin-1 Gene in Acute Myeloid Leukemia

Nucleophosmin-1 (NPM1) mutations represent the most frequent gene alteration in acute myeloid leukemia (AML). The most common NPM1 mutation type, accounting for 75 to 80% of cases, is referred to as mutation A (NPM1-mutA). These NPM1 alterations have been shown to possess prognostic significance bec...

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Main Authors: Ottone, Tiziana, Ammatuna, Emanuele, Lavorgna, Serena, Noguera, Nélida I., Buccisano, Francesco, Venditti, Adriano, Giannì, Laura, Postorino, Massimiliano, Federici, Giorgio, Amadori, Sergio, Lo-Coco, Francesco
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2008
主題:
Technical Advances
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329785/
https://ncbi.nlm.nih.gov/pubmed/18403613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.070166
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