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Nucleophosmin (NPM1) Mutations in Acute Myeloid Leukemia: An Ongoing (Cytoplasmic) Tale of Dueling Mutations and Duality of Molecular Genetic Testing Methodologies

This Commentary highlights two articles that focus on molecular techniques to identify mutations in nucleophosmin (NPM1), which is the most frequently mutated gene in cytogenetically normal acute myeloid leukemia (CN-AML)

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Hlavní autoři: Wertheim, Gerald, Bagg, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329783/
https://ncbi.nlm.nih.gov/pubmed/18403611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.080019
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