Sparse production but preferential incorporation of recently produced naïve T cells in the human peripheral pool

In mice, recent thymic emigrants (RTEs) make up a large part of the naïve T cell pool and have been suggested to be a distinct short-lived pool. In humans, however, the life span and number of RTEs are unknown. Although (2)H(2)O labeling in young mice showed high thymic-dependent daily naïve T cell...

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Detalhes bibliográficos
Main Authors: Vrisekoop, Nienke, den Braber, Ineke, de Boer, Anne Bregje, Ruiter, An F. C., Ackermans, Mariëtte T., van der Crabben, Saskia N., Schrijver, Elise H. R., Spierenburg, Gerrit, Sauerwein, Hans P., Hazenberg, Mette D., de Boer, Rob J., Miedema, Frank, Borghans, José A. M., Tesselaar, Kiki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329696/
https://ncbi.nlm.nih.gov/pubmed/18420820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709713105
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