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Cardiogenic small molecules that enhance myocardial repair by stem cells

The clinical success of stem cell therapy for myocardial repair hinges on a better understanding of cardiac fate mechanisms. We have identified small molecules involved in cardiac fate by screening a chemical library for activators of the signature gene Nkx2.5, using a luciferase knockin bacterial a...

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Detalhes bibliográficos
Main Authors: Sadek, Hesham, Hannack, Britta, Choe, Elizabeth, Wang, Jessica, Latif, Shuaib, Garry, Mary G., Garry, Daniel J., Longgood, Jamie, Frantz, Doug E., Olson, Eric N., Hsieh, Jenny, Schneider, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329693/
https://ncbi.nlm.nih.gov/pubmed/18420817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711507105
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