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Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression

In the central nervous system (CNS), neural stem cells (NSCs) differentiate into neurons, astrocytes, and oligodendrocytes - these cell lineages are considered unidirectional and irreversible under normal conditions. The introduction of a defined set of transcription factors has been shown to direct...

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Detalhes bibliográficos
Main Authors: Zhang, Ling, Li, Peng, Hsu, Tiffany, Aguilar, Hector R., Frantz, Doug E., Schneider, Jay W., Bachoo, Robert M., Hsieh, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752777/
https://ncbi.nlm.nih.gov/pubmed/21419563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2011.02.005
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