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Nanoconjugate based on polymalic acid for tumor targeting

A new prototype of polymer-derived drug delivery system, the nanoconjugate Polycefin, was tested for its ability to accumulate in tumors based on enhanced permeability and retention (EPR) effect and receptor mediated endocytosis. Polycefin was synthesized for targeted delivery of Morpholino antisens...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ljubimova, Julia Y., Fujita, Manabu, Khazenzon, Natalya M., Lee, Bong-Seop, Wachsmann-Hogiu, Sebastian, Farkas, Daniel L., Black, Keith L., Holler, Eggehard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329596/
https://ncbi.nlm.nih.gov/pubmed/17376417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2007.01.015
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