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Insulin Stimulates Primary β-Cell Proliferation via Raf-1 Kinase

A relative decrease in β-cell mass is key in the pathogenesis of type 1 diabetes, type 2 diabetes, and in the failure of transplanted islet grafts. It is now clear that β-cell duplication plays a dominant role in the regulation of adult β-cell mass. Therefore, knowledge of the endogenous regulators...

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Bibliografische gegevens
Hoofdauteurs: Beith, Jennifer L., Alejandro, Emilyn U., Johnson, James D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Endocrine Society 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329266/
https://ncbi.nlm.nih.gov/pubmed/18202127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1557
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