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Homoazasterol-mediated inhibition of yeast sterol biosynthesis.

A naturally occurring azasterol has been shown to inhibit sterol transmethylation in both in vitro and in vivo in the yeast Saccharomyces cerevisiae. The inhibition was competitive, with a calculated dissociation constant of 43 muM. The compound prevented the accumulation of ergosterol in aerobicall...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Bailey, R B, Hays, P R, Parks, L W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1976
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/791927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.128.3.730-734.1976
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