Homoazasterol-mediated inhibition of yeast sterol biosynthesis.
A naturally occurring azasterol has been shown to inhibit sterol transmethylation in both in vitro and in vivo in the yeast Saccharomyces cerevisiae. The inhibition was competitive, with a calculated dissociation constant of 43 muM. The compound prevented the accumulation of ergosterol in aerobicall...
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| Udgivet i: | J Bacteriol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1976
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/791927/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.128.3.730-734.1976 |
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