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Sterol Uptake in Saccharomyces cerevisiae Heme Auxotrophic Mutants Is Affected by Ergosterol and Oleate but Not by Palmitoleate or by Sterol Esterification

The relationship between sterol uptake and heme competence in two yeast strains impaired in heme synthesis, namely, G204 and H12-6A, was analyzed. To evaluate heme availability, a heterologous 17α-hydroxylase cytochrome P-450 cDNA (P-450c17) was expressed in these strains, and its activity was measu...

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Detalhes bibliográficos
Main Authors: Ness, Frédérique, Achstetter, Tilman, Duport, Catherine, Karst, Francis, Spagnoli, Roberto, Degryse, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107107/
https://ncbi.nlm.nih.gov/pubmed/9537392
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