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HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

The karyophilic properties of the HIV-1 nucleoprotein complex facilitate infection of nondividing cells such as macrophages and quiescent T lymphocytes, and allow the in vivo delivery of transgenes by HIV-derived retroviral vectors into terminally differentiated cells such as neurons. Although the v...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gallay, Philippe, Hope, Thomas, Chin, Daniel, Trono, Didier
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275210/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9825
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