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Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans
In Caenorhabditis elegans, specific Argonaute proteins are dedicated to the RNAi and microRNA pathways. To uncover how the precise Argonaute selection occurs, we designed dsRNA triggers containing both miRNA and siRNA sequences. While dsRNA carrying nucleotides mismatches can only enter the miRNA pa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327357/ https://ncbi.nlm.nih.gov/pubmed/18367718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.901908 |
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