The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA–Argonaute complex—or miRNA-induced silencing complex (miRISC)—can regulate the translation of their targets in such diverse ways. We demonstrate here a direct interaction between the miRISC and the ribosome...

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Detalhes bibliográficos
Main Authors: Jannot, Guillaume, Bajan, Sarah, Giguère, Nellie J, Bouasker, Samir, Banville, Isabelle H, Piquet, Sandra, Hutvagner, Gyorgy, Simard, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128278/
https://ncbi.nlm.nih.gov/pubmed/21525958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.66
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