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Splicing regulation: From a parts list of regulatory elements to an integrated splicing code

Alternative splicing of pre-mRNAs is a major contributor to both proteomic diversity and control of gene expression levels. Splicing is tightly regulated in different tissues and developmental stages, and its disruption can lead to a wide range of human diseases. An important long-term goal in the s...

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Detalhes bibliográficos
Main Authors: Wang, Zefeng, Burge, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327353/
https://ncbi.nlm.nih.gov/pubmed/18369186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.876308
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