PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells

Earlier work has shown that the transcription factor C/EBPα induced a transdifferentiation of committed lymphoid precursors into macrophages in a process requiring endogenous PU.1. Here we have examined the effects of PU.1 and C/EBPα on fibroblasts, a cell type distantly related to blood cells and a...

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Main Authors: Feng, Ru, Desbordes, Sabrina C., Xie, Huafeng, Tillo, Ester Sanchez, Pixley, Fiona, Stanley, E. Richard, Graf, Thomas
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327209/
https://ncbi.nlm.nih.gov/pubmed/18424555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711961105
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