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Forced expression of terminal deoxynucleotidyl transferase in fetal thymus resulted in a decrease in γδ T cells and random dissemination of Vγ3Vδ1 T cells in skin of newborn but not adult mice
The repertoire of lymphocyte receptor genes encoded in a germline is further diversified by a number of processes, including the template-independent addition of nucleotides (N regions) by means of terminal deoxynucleotidyl transferase (TdT). Normally, mouse γδ T cells in the early fetal thymus, who...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327197/ https://ncbi.nlm.nih.gov/pubmed/10792495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00987.x |
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