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Forced expression of terminal deoxynucleotidyl transferase in fetal thymus resulted in a decrease in γδ T cells and random dissemination of Vγ3Vδ1 T cells in skin of newborn but not adult mice

The repertoire of lymphocyte receptor genes encoded in a germline is further diversified by a number of processes, including the template-independent addition of nucleotides (N regions) by means of terminal deoxynucleotidyl transferase (TdT). Normally, mouse γδ T cells in the early fetal thymus, who...

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Main Authors: Aono, A, Enomoto, H, Yoshida, N, Yoshizaki, K, Kishimoto, T, Komori, T
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327197/
https://ncbi.nlm.nih.gov/pubmed/10792495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00987.x
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