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An acidic microenvironment impairs the generation of non-major histocompatibility complex-restricted killer cells
The microenvironment within solid tumours has often been shown to exhibit an acidic local pH. In recent studies we could demonstrate that an acidic extracellular pH (pH(e)) inhibits the non-major histocompatibility complex (MHC) -restricted cytotoxicity of immunocompetent effector cells. However, wi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327168/ https://ncbi.nlm.nih.gov/pubmed/10712667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00975.x |
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