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Modulation of the immune response to DNA vaccine by co-delivery of costimulatory molecules

We have investigated methods for modulating immune responses, against herpes simplex virus (HSV), generated from DNA vaccination by co-delivery of genes encoding costimulatory molecules.A strong delayed-type hypersensitivity (DTH) reaction was induced in mice co-injected via the intradermal (i.d.) r...

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Autori principali: Fló, J, Tisminetzky, S, Baralle, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327003/
https://ncbi.nlm.nih.gov/pubmed/10886404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00041.x
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