Human antigen‐presenting cell/tumour cell hybrids stimulate strong allogeneic responses and present tumour‐associated antigens to cytotoxic T cells in vitro

Most tumours do not stimulate effective antitumour immune responses in vivo. In order to enhance the immunogenicity of human tumour cells, we fused a variety of tumour cell lines with an Epstein–Barr virus transformed B‐lymphoblastoid cell line (EBV B‐LCL) in vitro, to produce stable hybrid cells. H...

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Detalhes bibliográficos
Main Authors: Dunnion, D J, Cywinski, A L, Tucker, V C, Murray, A K, Rickinson, A B, Coulie, P, Browning, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326964/
https://ncbi.nlm.nih.gov/pubmed/10594686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00912.x
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