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Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus

How the fetus escapes rejection by the maternal immune system remains one of the major unsolved questions in transplantation immunology. Using a system to visualize both CD4(+) and CD8(+) T cell responses during pregnancy in mice, we find that maternal T cells become aware of the fetal allograft exc...

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Detalhes bibliográficos
Main Authors: Erlebacher, Adrian, Vencato, Daniela, Price, Kelly A., Zhang, Dorothy, Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849983/
https://ncbi.nlm.nih.gov/pubmed/17446933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28214
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