Nitric oxide selectively decreases interferon‐γ expression by activated human T lymphocytes via a cGMP‐independent mechanism

The role of exogenous nitric oxide (NO) on the expression of interleukin (IL)‐2, IL‐4, IL‐5 and interferon‐γ (IFN‐γ) by freshly isolated human T lymphocytes was investigated. The presence of NO, generated from any of the NO‐donor compounds, S‐nitroso‐N‐acetyl‐d,l‐penicillamine (SNAP), DPTA‐nonoate (...

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Detalhes bibliográficos
Main Authors: Roozendaal, R, Vellenga, E, Postma, D S, De Monchy, J G R, Kauffman, H F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326937/
https://ncbi.nlm.nih.gov/pubmed/10583599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00895.x
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