Interleukin-12-secreting fibroblasts are more efficient than free recombinant interleukin-12 in inducing the persistent resistance to Mycobacterium avium complex infection

To determine whether the paracrine secretion of interleukin-12 (IL-12) can efficiently stimulate the resistance to Mycobacterium avium complex (MAC) infection, 3T3 fibroblasts were stably transfected to secrete IL-12 (480 U/10(6) cells/48 hr) and their effect on MAC infection was investigated in gen...

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Detalhes bibliográficos
Main Authors: Kang, B Y, Chung, S W, Lim, Y S, Kim, E J, Kim, S H, Hwang, S Y, Kim, T S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326848/
https://ncbi.nlm.nih.gov/pubmed/10447770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00796.x
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