Protection of mice from Mycobacterium avium infection by recombinant interleukin-12.

Treatment with interleukin-12 (IL-12) significantly reduced the number of viable bacteria in mice infected with Mycobacterium avium. IL-12 itself, however, could not inhibit directly mycobacterial growth in vitro. IL-12 exerts antimycobacterial activity in vivo with a low level of toxicity, possibly...

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Detalhes bibliográficos
Main Authors: Kobayashi, K, Kasama, T, Yamazaki, J, Hosaka, M, Katsura, T, Mochizuki, T, Soejima, K, Nakamura, R M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162744/
https://ncbi.nlm.nih.gov/pubmed/7574533
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