Protection of mice from Mycobacterium avium infection by recombinant interleukin-12.

Treatment with interleukin-12 (IL-12) significantly reduced the number of viable bacteria in mice infected with Mycobacterium avium. IL-12 itself, however, could not inhibit directly mycobacterial growth in vitro. IL-12 exerts antimycobacterial activity in vivo with a low level of toxicity, possibly...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kobayashi, K, Kasama, T, Yamazaki, J, Hosaka, M, Katsura, T, Mochizuki, T, Soejima, K, Nakamura, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1369
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