p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.
The tumor suppressor protein p53 acts as a transcriptional activator that can mediate cellular responses to DNA damage by inducing apoptosis and cell cycle arrest. p53 is a nuclear phosphoprotein, and phosphorylation has been proposed to be a means by which the activity of p53 is regulated. The cycl...
Uloženo v:
| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7220 |
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