p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.

The tumor suppressor protein p53 acts as a transcriptional activator that can mediate cellular responses to DNA damage by inducing apoptosis and cell cycle arrest. p53 is a nuclear phosphoprotein, and phosphorylation has been proposed to be a means by which the activity of p53 is regulated. The cycl...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Ko, L J, Shieh, S Y, Chen, X, Jayaraman, L, Tamai, K, Taya, Y, Prives, C, Pan, Z Q
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7220
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