p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.

The tumor suppressor protein p53 acts as a transcriptional activator that can mediate cellular responses to DNA damage by inducing apoptosis and cell cycle arrest. p53 is a nuclear phosphoprotein, and phosphorylation has been proposed to be a means by which the activity of p53 is regulated. The cycl...

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Detalhes bibliográficos
Main Authors: Ko, L J, Shieh, S Y, Chen, X, Jayaraman, L, Tamai, K, Taya, Y, Prives, C, Pan, Z Q
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC232579/
https://ncbi.nlm.nih.gov/pubmed/9372954
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