Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.
Thyroid hormone receptor (T3R) is a member of the steroid hormone receptor gene family of nuclear hormone receptors. In most cells T3R activates gene expression only in the presence of its ligand, L-triiodothyronine (T3). However, in certain cell types (e.g., GH4C1 cells) expression of T3R leads to...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7195 |
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