Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.

Thyroid hormone receptor (T3R) is a member of the steroid hormone receptor gene family of nuclear hormone receptors. In most cells T3R activates gene expression only in the presence of its ligand, L-triiodothyronine (T3). However, in certain cell types (e.g., GH4C1 cells) expression of T3R leads to...

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Publicado en:	Mol Cell Biol
Autores principales:	Qi, J S, Desai-Yajnik, V, Yuan, Y, Samuels, H H
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7195
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