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Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes.

Human nucleotide excision repair processes carcinogen-DNA adducts at highly variable rates, even at adjacent sites along individual genes. Here, we identify conformational determinants of fast or slow repair by testing excision of N2-guanine adducts formed by benzo[a]pyrene diol epoxide (BPDE), a po...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Hess, M T, Gunz, D, Luneva, N, Geacintov, N E, Naegeli, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1997
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372938/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7069
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