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Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

The Bcl-2 related protein Bad is a promoter of apoptosis and has been shown to dimerize with the anti-apoptotic proteins Bcl-2 and Bcl-XL. Overexpression of Bad in murine FL5.12 cells demonstrated that the protein not only could abrogate the protective capacity of coexpressed Bcl-XL but could accele...

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Autors principals: Kelekar, A, Chang, B S, Harlan, J E, Fesik, S W, Thompson, C B
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC232560/
https://ncbi.nlm.nih.gov/pubmed/9372935
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