Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB.

Manganese superoxide dismutase (MnSOD), a tumor necrosis factor (TNF)-inducible reactive oxygen-scavenging enzyme, protects cells from TNF-mediated apoptosis. To understand how MnSOD is regulated, transient transfections of promoter-reporter gene constructions, in vitro DNA binding assays, and in vi...

Celý popis

Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Jones, P L, Ping, D, Boss, J M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.6970
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!