RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution.
V(D)J recombination is initiated by RAG-1 and RAG-2, which introduce double-strand DNA breaks at recombination signal sequences (RSSs) of antigen receptor gene segments to produce signal ends, terminating in blunt, double-strand breaks, and coding ends, terminating in DNA hairpins. While the formati...
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| Vydáno v: | Mol Cell Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372925/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.6932 |
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