A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis.

Upon activation, cell surface death receptors, Fas/APO-1/CD95 and tumor necrosis factor receptor-1 (TNFR-1), are attached to cytosolic adaptor proteins, which in turn recruit caspase-8 (MACH/FLICE/Mch5) to activate the interleukin-1 beta-converting enzyme (ICE)/CED-3 family protease (caspase) cascad...

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Autores principales: Kagaya, S, Kitanaka, C, Noguchi, K, Mochizuki, T, Sugiyama, A, Asai, A, Yasuhara, N, Eguchi, Y, Tsujimoto, Y, Kuchino, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC232528/
https://ncbi.nlm.nih.gov/pubmed/9343438
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