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Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.

Activation of the tyrosine kinase JAK2 is an essential step in cellular signaling by growth hormone (GH) and multiple other hormones and cytokines. Murine JAK2 has a total of 49 tyrosines which, if phosphorylated, could serve as docking sites for Src homology 2 (SH2) or phosphotyrosine binding domai...

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Tallennettuna:
Julkaisussa:Mol Cell Biol
Päätekijät: Rui, L, Mathews, L S, Hotta, K, Gustafson, T A, Carter-Su, C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343427/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.11.6633
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