Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase.

Gamma interferon (IFN-gamma) induces both tyrosine and serine phosphorylation of Stat1. Stat1 serine phosphorylation is required for maximal transcriptional activity of Stat1. In this report, we present evidence that Stat1 tyrosine phosphorylation is not a prerequisite for Stat1 serine phosphorylati...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Zhu, X, Wen, Z, Xu, L Z, Darnell, J E
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.11.6618
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