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Blockade of T-cell activation by dithiocarbamates involves novel mechanisms of inhibition of nuclear factor of activated T cells.

Dithiocarbamates (DTCs) have recently been reported as powerful inhibitors of NF-kappaB activation in a number of cell types. Given the role of this transcription factor in the regulation of gene expression in the inflammatory response, NF-kappaB inhibitors have been suggested as potential therapeut...

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Bibliografske podrobnosti
Main Authors: Martínez-Martínez, S, Gómez del Arco, P, Armesilla, A L, Aramburu, J, Luo, C, Rao, A, Redondo, J M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC232496/
https://ncbi.nlm.nih.gov/pubmed/9343406
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